Nursing & Healthcare Directories on: The Nursefriendly
Prescription Drugs, Medications, Medicines
Nutritional Supplements, Vitamins & Minerals,
Cyanocobalamin, Vitamin B12

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Nascobal Nasal Gel, Drug Interactions, aHealthyMe.com:"Tell your doctor of all nonprescription and prescription medication you may use, especially of: colchicine, para-aminosalicylic acid. Also report the use of drugs that can affect blood cell production such as: anti-cancer drugs, chloramphenicol, zidovudine, ganciclovir. Methotrexate, pyrimethamine and certain antibiotics may interfere with folic acid and vitamin B12 blood test results. Do not start or stop any medicine without doctor or pharmacist approval."
http://www.ahealthyme.com/viewmonograph;$sessionid$ILSMS2YAABJSWCTYAITDEMQ?selectedDrugId=269929&selectedDrugDescription=Nascobal+Nasal+Gel+500+mcg%2F0.1+mL

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Cyanocobalamin Nasal, What side effects should I look for, Drug Digest:"Headache, nausea, dizziness or nasal congestion may occur. If these persist or worsen, notify your doctor. Side effects very unlikely to occur are muscle cramping or weakness, leg or arm swelling or pain, or tingling of the hands or feet and should be reported to your doctor. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms include rash, itching, swelling, dizziness or trouble breathing."
http://www.drugdigest.org/DD/DVH/SideEffects/0,3917,6077|Cyanocobalamin%2Bnasal,00.html

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Cyanocobalamin Nasal, What is cyanocobalamin nasal, Drugs.com":"Cyanocobalamin nasal is a synthetic (man-made) form of vitamin B12. Vitamin B12 is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.

Cyanocobalamin nasal is used to maintain vitamin B12 levels in patients with pernicious anemia, nutritional vitamin B12 deficiency, malabsorption of vitamin B12, and other cases of vitamin B12 deficiency."
http://www.drugs.com/xq/cfm/pageID_0/htm_d04278A1.htm/bn_cyanocobalamin%20nasal/qx/index.htm

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Nascobal, Directions, Drugstore.com:"Follow the directions for using this medicine provided by your doctor. This medicine is used in the nose. This medicine comes with a patient information leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. DO NOT USE THIS MEDICINE within 1 hour of eating or drinking hot foods or liquids. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT use 2 doses at once."
http://www.drugstore.com/qxn00091703313_333181_sespider/nascobal/nascobal.htm

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Cyanocobalamin, Description, Familydoctor.org:"What is the most important information I should know about cyanocobalamin? • To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life. Failure to do this will result in irreversible damage to the nerves of your spinal cord. Also, treatment with cyanocobalamin cannot be substituted with folic acid therapy. Folic acid may prevent anemia but it will allow progressive damage to the spinal cord. • Use the nasal spray one hour before or after eating or drinking hot foods or liquids. What is cyanocobalamin? • Cyanocobalamin is a synthetic (man-made) form of vitamin B12. Vitamin B12 is important for growth, cell reproduction, blood formation, and protein and tissue synthesis. • Cyanocobalamin is used to treat pernicious anemia, nutritional vitamin B12 deficiency, malabsorption of vitamin B12, and other cases of vitamin B12 deficiency. • Cyanocobalamin may also be used for purposes other than those listed in this medication guide."
Director Online Content Management, American Academy of Family Physicians
11400 Tomahawk Creek Parkway Leawood, KS 66211-2672
E-mail: email@familydoctor.org
http://www.familydoctor.org/cgi-bin/multum.pl?op=GetLeaflet&id=14237&name=vitamin%20B12 ******************************************************

Vitamin B12, Anemia, Healthsquare.com:"There are several methods of treatment for anemia, depending upon the severity of the condition and how rapidly blood is being lost. Not all cases are curable. If the condition is severe, a blood transfusion is the only treatment available. However, in less severe cases, the problem can be remedied by other means. Typical treatments for specific forms of anemia are as follows. Iron-deficiency anemia: Treatment to halt any underlying hidden bleeding, plus iron supplements, usually taken orally between meals. Pernicious anemia: Regular injections of vitamin B12. (Injections are needed because of the body's inability to absorb the vitamin through the digestive tract.)"
New Media Systems, LLC
Jefferson Square Building 621 Shrewsbury Avenue Shrewsbury, NJ 07702
Phone: (732) 212-9191 Fax (732) 212-1260 Email: rcollado@nmspartners.com
http://www.healthsquare.com/mc/fgmc9005.htm

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VITAMIN B 12 (Systemic), Overview, MEDLINE Plus:"Increased need for vitamin B (sub 12) should be determined by your health care professional. Lack of vitamin B (sub 12) may lead to anemia (weak blood), stomach problems, and nerve damage. Your health care professional may treat this by prescribing vitamin B (sub 12) for you."
Office of Communications and Public Liaison, National Library of Medicine
8600 Rockville Pike Bethesda, Maryland 20894 Phone: (301) 496-6308 Fax: (301) 496-4450
email: publicinfo@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202596.html

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Vitamin B 12 (Systemic), Pregnancy, MEDLINEplus:"It is especially important that you are receiving enough vitamins when you become pregnant and that you continue to receive the right amount of vitamins throughout your pregnancy. Healthy fetal growth and development depend on a steady supply of nutrients from mother to fetus. However, taking large amounts of a dietary supplement in pregnancy may be harmful to the mother and/or fetus and should be avoided.

You may need vitamin B 12 supplements if you are a strict vegetarian (vegan-vegetarian). Too little vitamin B 12 can cause harmful effects such as anemia or nervous system injury."
U.S. National Library of Medicine
8600 Rockville Pike, Bethesda, MD 20894
custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202596.html

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Hydroxocobalamin, Cyanide Disasters, National Center For Biotechnology Information:"Hydroxocobalamin is well recognized as an efficacious, safe, and easily administered cyanide antidote. Because of its extremely low adverse effect profile, it is ideal for out-of-hospital use in suspected cyanide intoxication. To effectively prepare for a cyanide disaster, the United States must investigate, adopt, manufacture, and stockpile hydroxocobalamin to prevent needless morbidity and mortality."
National Center for Biotechnology Information, U.S. National Library of Medicine
8600 Rockville Pike Bethesda, MD 20894
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11385334&dopt=Abstract

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Hydroxocobalamin, (Vitamin B12b), Anti-HIV Research, National Institute Of Allergy and Infectious Diseases:"Hydroxocobalamin, methylcobalamin, 5'-deoxyadenosylcobalamin, and dicyanocobinamide inhibited HIV production in normal human blood monocytes and lymphocytes(1,2). Inhibition was more cell specific than viral strain specific, cobalamins were much less effective in cell lines such as Jurkat and CEM than in normal human monocytes and lymphocytes. Cyanocobalamin, vitamin B12, however, did not significantly inhibit HIV-1 replication below 1000 µM (1). HIV-1 integrase has been shown to be a potential target of cobalamins (2)."
NIAID
Building 31, Room 7A-50 31 Center Drive MSC 2520 Bethesda, MD 20892-2520
http://www.niaid.nih.gov/daids/dtpdb/028454.htm

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Vitamin B12, Dietary Sources, National Institutes Of Health Clinical Center:"What foods provide vitamin B12? Vitamin B12 is naturally found in animal foods including fish, milk and milk products, eggs, meat, and poultry. Fortified breakfast cereals are an excellent source of vitamin B12 and a particularly valuable source for vegetarians."
Clinical Center Communications
6100 Executive Blvd., Suite 3C01 MSC 7511 Bethesda, Maryland 20892-7511
Phone: 301-496-2563 Fax: 301-402-2984 E-mail: OCCC@cc.nih.gov
http://www.cc.nih.gov/ccc/supplements/vitb12.html

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Cyanocobalamin Nasal, Who should not use cyanocobalamin nasal, Northwestern Memorial Hospital:"Before using this medication, tell your doctor if you have Leber's disease. Cyanocobalamin nasal may lead to optic nerve damage and possibly blindness when used by people with this condition.

When using the nasal spray, tell your doctor if you develop nasal congestion, a cold, or allergies. The nasal spray may not work as well if you are congested.

Cyanocobalamin nasal is in the FDA pregnancy category C. This means that it is not known whether cyanocobalamin nasal will harm an unborn baby. Vitamin B12 is important to the proper development of a baby. Talk to your doctor about using this medication if you are pregnant.

Cyanocobalamin nasal passes into breast milk. Vitamin B12 is necessary for both mother and child during breast-feeding. Talk to your doctor about using this medication during breast-feeding."
http://health_info.nmh.org/Library/HealthGuide/DrugGuide/topic.asp?hwid=multumd04278a1

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Cyanocobalamin (Vitamin B12), Action/Kinetics, Nurses's PDR Resource Center:"Required for hematopoiesis, cell reproduction, nucleoprotein and myelin synthesis. Plasma vitamin B12 levels: 150-750 pg/mL. Rapidly absorbed following IM or SC administration. Following absorption, vitamin B12 is carried by plasma proteins to the liver where it is stored until required for various metabolic functions. t1/2: 6 days (400 days in the liver). Time to peak levels, after PO: 8-12 hr."
Thomson Learning - Customer Service
PO Box 6904 Florence, KY 41022-6904
Phone: (800)-354-9706 Fax: (800)-487-8488 Email: esales@thomsonlearning.com
http://www.nursespdr.com/members/database/ndrhtml/cyanocobalamin.html

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Hydroxocobalamin (Injectable), Side Effects, PersonalMD.com:"Mild diarrhea, itching, or a feeling of general swelling may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these unlikely but serious side effects occur: pain in the groin or lower legs, trouble breathing, swelling of the hands and feet, unusual weakness/fatigue, chest pain. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, severe swelling, dizziness. If you notice other effects not listed above, contact your doctor or pharmacist."
PersonalMD.com
4725 First Street Suite 275 Pleasanton, CA 94566
Phone: 925 417 6840 Fax: 925 600 7568
http://www.personalmd.com/drgdb/5343.htm

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Cyanocobalamin-Nasal, Precautions, PersonalMd.com:"Before using this drug, tell your doctor your medical history, including: Leber's disease (an eye problem), allergies (especially drug or food allergies). Do not use folic acid in place of vitamin B12 treatments. Limit alcohol use as it may affect the level of vitamin B12 in your body. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor."
http://www.personalmd.com/drgdb/9288.htm

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Cyanocobalamin Nasal, What is the most important information I should know about cyanocobalamin nasal, Subscriberx.com:"To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life. Failure to do this will result in irreversible damage to the nerves of your spinal cord. Also, treatment with cyanocobalamin nasal cannot be substituted with folic acid therapy. Folic acid may prevent anemia but it will allow progressive damage to the spinal cord.

Use the nasal spray one hour before or after eating or drinking hot foods or liquids."
http://www.subscriberx.com/.SRX?Service=SRXLeaflet&Function=GetLeaflet&DrugId=13824&Dialect=English

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Vitamin B12 (Cyanocobalamin), Range and Frequency, Whole Health Md:"Recommended dietary allowances (RDAs)— Adults and teenagers: 2.4 micrograms (mcg). Pregnant or breast-feeding women: 2.6 to 2.8 mcg. Children ages 9 to 13: 1.8 mcg. Children ages 4 to 8: 1.2 mcg. From birth to 3 years of age: 0.4 to 0.9 mcg. (Extended-release tablets are not recommended for children.) To treat severe vitamin B12 deficiency— The dose will be determined by your doctor based on individual criteria. Patients with pernicious anemia or loss of intestinal function require the injection form of vitamin B12. As an alternative to the injection, patients may use the nasal gel with a dose of 500 mcg, once a week."
http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,640,00.html

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Nurses' Station:"The idea for the Nurses' Station Catalog was conceived in 1989. After searching the marketplace in response to customer inquiries, it became obvious that there were no catalogs of this type serving the nursing profession. To be sure, there were several catalogs offering nurse's uniforms and a smattering of professional items. But there weren't any catalogs at the time offering a range of gifts, clothing, professional items, name badges, shoes and scrubs for nurses. It took two years of hard work to gather samples and put a together a catalog of the most unique and high-quality items for nurses."
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