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This page was prepared by Lynn Kash, RN, Internet Nursing Guide
Pennsylvania Nurses,Emergency Department
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Nascobal Nasal Gel, Drug Interactions, aHealthyMe.com:"Tell your doctor of all nonprescription and prescription medication you may use, especially of: colchicine, para-aminosalicylic acid. Also report the use of drugs that can affect blood cell production such as: anti-cancer drugs, chloramphenicol, zidovudine, ganciclovir. Methotrexate, pyrimethamine and certain antibiotics may interfere with folic acid and vitamin B12 blood test results. Do not start or stop any medicine without doctor or pharmacist approval."
http://www.ahealthyme.com/viewmonograph;$sessionid$ILSMS2YAABJSWCTYAITDEMQ?selectedDrugId=269929&selectedDrugDescription=Nascobal+Nasal+Gel+500+mcg%2F0.1+mL
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Cyanocobalamin Nasal, What side effects should I look for, Drug Digest:"Headache, nausea, dizziness or nasal congestion may occur. If these persist or worsen, notify your doctor. Side effects very unlikely to occur are muscle cramping or weakness, leg or arm swelling or pain, or tingling of the hands or feet and should be reported to your doctor. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms include rash, itching, swelling, dizziness or trouble breathing."
http://www.drugdigest.org/DD/DVH/SideEffects/0,3917,6077|Cyanocobalamin%2Bnasal,00.html
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Cyanocobalamin Nasal, What is cyanocobalamin nasal, Drugs.com":"Cyanocobalamin nasal is a synthetic (man-made) form of vitamin B12. Vitamin B12 is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.
Cyanocobalamin nasal is used to maintain vitamin B12 levels in patients with pernicious anemia, nutritional vitamin B12 deficiency, malabsorption of vitamin B12, and other cases of vitamin B12 deficiency."
http://www.drugs.com/xq/cfm/pageID_0/htm_d04278A1.htm/bn_cyanocobalamin%20nasal/qx/index.htm
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Nascobal, Directions, Drugstore.com:"Follow the directions for using this medicine provided by your doctor. This medicine is used in the nose. This medicine comes with a patient information leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. DO NOT USE THIS MEDICINE within 1 hour of eating or drinking hot foods or liquids. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT use 2 doses at once."
http://www.drugstore.com/qxn00091703313_333181_sespider/nascobal/nascobal.htm
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Cyanocobalamin, Description, Familydoctor.org:"What is the most important
information I should know about cyanocobalamin?
• To treat pernicious anemia, you will have to use this medication on
a regular basis for the rest of your life. Failure to do this will
result in irreversible damage to the nerves of your spinal cord.
Also, treatment with cyanocobalamin cannot be substituted with folic
acid therapy. Folic acid may prevent anemia but it will allow
progressive damage to the spinal cord.
• Use the nasal spray one hour before or after eating or drinking hot
foods or liquids.
What is cyanocobalamin?
• Cyanocobalamin is a synthetic (man-made) form of vitamin B12.
Vitamin B12 is important for growth, cell reproduction, blood
formation, and protein and tissue synthesis.
• Cyanocobalamin is used to treat pernicious anemia, nutritional
vitamin B12 deficiency, malabsorption of vitamin B12, and other cases
of vitamin B12 deficiency.
• Cyanocobalamin may also be used for purposes other than those listed
in this medication guide."
Director Online Content Management,
American Academy of Family Physicians
11400 Tomahawk Creek Parkway
Leawood, KS
66211-2672
E-mail: email@familydoctor.org
http://www.familydoctor.org/cgi-bin/multum.pl?op=GetLeaflet&id=14237&name=vitamin%20B12
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Vitamin B12, Anemia, Healthsquare.com:"There are several methods of
treatment for anemia, depending upon the severity of the condition and
how rapidly blood is being lost. Not all cases are curable. If the
condition is severe, a blood transfusion is the only treatment available.
However, in less severe cases, the problem can be remedied by other means.
Typical treatments for specific forms of anemia are as follows.
Iron-deficiency anemia: Treatment to halt any underlying hidden bleeding,
plus iron supplements, usually taken orally between meals.
Pernicious anemia: Regular injections of vitamin B12. (Injections are
needed because of the body's inability to absorb the vitamin through
the digestive tract.)"
New Media Systems, LLC
Jefferson Square Building
621 Shrewsbury Avenue
Shrewsbury, NJ 07702
Phone: (732) 212-9191
Fax (732) 212-1260
Email: rcollado@nmspartners.com
http://www.healthsquare.com/mc/fgmc9005.htm
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VITAMIN B 12 (Systemic), Overview, MEDLINE Plus:"Increased need for
vitamin B (sub 12) should be determined by your health care professional.
Lack of vitamin B (sub 12) may lead to anemia (weak blood), stomach
problems, and nerve damage. Your health care professional may treat this
by prescribing vitamin B (sub 12) for you."
Office of Communications and Public Liaison,
National Library of Medicine
8600 Rockville Pike
Bethesda, Maryland 20894
Phone: (301) 496-6308
Fax: (301) 496-4450
email: publicinfo@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202596.html
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Vitamin B 12 (Systemic), Pregnancy, MEDLINEplus:"It is especially important that you are receiving enough vitamins when you become pregnant and that you continue to receive the right amount of vitamins throughout your pregnancy. Healthy fetal growth and development depend on a steady supply of nutrients from mother to fetus. However, taking large amounts of a dietary supplement in pregnancy may be harmful to the mother and/or fetus and should be avoided.
You may need vitamin B 12 supplements if you are a strict vegetarian (vegan-vegetarian). Too little vitamin B 12 can cause harmful effects such as anemia or nervous system injury."
U.S. National Library of Medicine
8600 Rockville Pike, Bethesda, MD 20894
custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202596.html
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Hydroxocobalamin, Cyanide Disasters, National Center For Biotechnology
Information:"Hydroxocobalamin is well recognized as an efficacious, safe,
and easily administered cyanide antidote. Because of its extremely low
adverse effect profile, it is ideal for out-of-hospital use in suspected
cyanide intoxication. To effectively prepare for a cyanide disaster, the
United States must investigate, adopt, manufacture, and stockpile
hydroxocobalamin to prevent needless morbidity and mortality."
National Center for Biotechnology Information,
U.S. National Library of Medicine
8600 Rockville Pike
Bethesda, MD 20894
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11385334&dopt=Abstract
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Hydroxocobalamin, (Vitamin B12b), Anti-HIV Research, National Institute
Of Allergy and Infectious Diseases:"Hydroxocobalamin, methylcobalamin,
5'-deoxyadenosylcobalamin, and dicyanocobinamide inhibited HIV production
in normal human blood monocytes and lymphocytes(1,2). Inhibition was more
cell specific than viral strain specific, cobalamins were much less
effective in cell lines such as Jurkat and CEM than in normal human
monocytes and lymphocytes. Cyanocobalamin, vitamin B12, however, did not
significantly inhibit HIV-1 replication below 1000 µM (1). HIV-1
integrase has been shown to be a potential target of cobalamins (2)."
NIAID
Building 31, Room 7A-50
31 Center Drive MSC 2520
Bethesda, MD 20892-2520
http://www.niaid.nih.gov/daids/dtpdb/028454.htm
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Vitamin B12, Dietary Sources, National Institutes Of Health Clinical
Center:"What foods provide vitamin B12?
Vitamin B12 is naturally found in animal foods including fish, milk and
milk products, eggs, meat, and poultry. Fortified breakfast cereals are
an excellent source of vitamin B12 and a particularly valuable source
for vegetarians."
Clinical Center Communications
6100 Executive Blvd., Suite 3C01
MSC 7511
Bethesda, Maryland 20892-7511
Phone: 301-496-2563
Fax: 301-402-2984
E-mail: OCCC@cc.nih.gov
http://www.cc.nih.gov/ccc/supplements/vitb12.html
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Cyanocobalamin Nasal, Who should not use cyanocobalamin nasal, Northwestern Memorial Hospital:"Before using this medication, tell your doctor if you have Leber's disease. Cyanocobalamin nasal may lead to optic nerve damage and possibly blindness when used by people with this condition.
When using the nasal spray, tell your doctor if you develop nasal congestion, a cold, or allergies. The nasal spray may not work as well if you are congested.
Cyanocobalamin nasal is in the FDA pregnancy category C. This means that it is not known whether cyanocobalamin nasal will harm an unborn baby. Vitamin B12 is important to the proper development of a baby. Talk to your doctor about using this medication if you are pregnant.
Cyanocobalamin nasal passes into breast milk. Vitamin B12 is necessary for both mother and child during breast-feeding. Talk to your doctor about using this medication during breast-feeding."
http://health_info.nmh.org/Library/HealthGuide/DrugGuide/topic.asp?hwid=multumd04278a1
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Cyanocobalamin (Vitamin B12), Action/Kinetics, Nurses's PDR Resource
Center:"Required for hematopoiesis, cell reproduction, nucleoprotein
and myelin synthesis. Plasma vitamin B12 levels: 150-750 pg/mL. Rapidly
absorbed following IM or SC administration. Following absorption,
vitamin B12 is carried by plasma proteins to the liver where it is stored
until required for various metabolic functions. t1/2: 6 days (400 days
in the liver). Time to peak levels, after PO: 8-12 hr."
Thomson Learning - Customer Service
PO Box 6904
Florence, KY 41022-6904
Phone: (800)-354-9706
Fax: (800)-487-8488
Email: esales@thomsonlearning.com
http://www.nursespdr.com/members/database/ndrhtml/cyanocobalamin.html
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Hydroxocobalamin (Injectable), Side Effects, PersonalMD.com:"Mild
diarrhea, itching, or a feeling of general swelling may occur. If any of
these effects persist or worsen, notify your doctor. Tell your doctor
immediately if any of these unlikely but serious side effects occur:
pain in the groin or lower legs, trouble breathing, swelling of the
hands and feet, unusual weakness/fatigue, chest pain. An allergic
reaction to this drug is unlikely, but seek immediate medical attention
if it occurs. Symptoms of an allergic reaction include: rash, severe
swelling, dizziness. If you notice other effects not listed above,
contact your doctor or pharmacist."
PersonalMD.com
4725 First Street
Suite 275
Pleasanton, CA 94566
Phone: 925 417 6840
Fax: 925 600 7568
http://www.personalmd.com/drgdb/5343.htm
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Cyanocobalamin-Nasal, Precautions, PersonalMd.com:"Before using this drug, tell your doctor your medical history, including: Leber's disease (an eye problem), allergies (especially drug or food allergies). Do not use folic acid in place of vitamin B12 treatments. Limit alcohol use as it may affect the level of vitamin B12 in your body. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor."
http://www.personalmd.com/drgdb/9288.htm
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Cyanocobalamin Nasal, What is the most important information I should know about cyanocobalamin nasal, Subscriberx.com:"To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life. Failure to do this will result in irreversible damage to the nerves of your spinal cord. Also, treatment with cyanocobalamin nasal cannot be substituted with folic acid therapy. Folic acid may prevent anemia but it will allow progressive damage to the spinal cord.
Use the nasal spray one hour before or after eating or drinking hot foods or liquids."
http://www.subscriberx.com/.SRX?Service=SRXLeaflet&Function=GetLeaflet&DrugId=13824&Dialect=English
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Vitamin B12 (Cyanocobalamin), Range and Frequency, Whole Health Md:"Recommended dietary allowances (RDAs)— Adults and teenagers: 2.4 micrograms (mcg). Pregnant or breast-feeding women: 2.6 to 2.8 mcg. Children ages 9 to 13: 1.8 mcg. Children ages 4 to 8: 1.2 mcg. From birth to 3 years of age: 0.4 to 0.9 mcg. (Extended-release tablets are not recommended for children.) To treat severe vitamin B12 deficiency— The dose will be determined by your doctor based on individual criteria. Patients with pernicious anemia or loss of intestinal function require the injection form of vitamin B12. As an alternative to the injection, patients may use the nasal gel with a dose of 500 mcg, once a week."
http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,640,00.html
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Yes! You read it correctly, it is legal to import a 90 day supply of medications without a prescription. More and more people everyday are turning to this hot new method of obtaining prescription drugs. This new method is fast, easy, and can save you up to 80% off of your regular drug costs!
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