Nursing & Healthcare Directories on: The Nursefriendly
Prescription Drugs, Medications, Medicines
Asthma, Bronchodilators, Respiratory,
Intal, Cromolyn Sodium

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This page was prepared by Lynn Kash, RN, Internet Nursing Guide
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Intal, Who is this for, Drug Digest:"Cromolyn is used to prevent the wheezing, shortness of breath, and troubled breathing caused by asthma. It also is used to prevent breathing difficulties (bronchospasm) during exercise. It works by preventing the release of substances that cause inflammation (swelling) in the air passages of the lungs. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information."
http://www.drugdigest.org/DD/DVH/Uses/0,3915,175|Intal,00.html

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What is cromolyn sodium inhalation, Drugs.com:"Cromolyn sodium is an anti-inflammatory medication. It works by preventing the release of substances in the body that cause inflammation.

Cromolyn sodium is used as an inhalant to prevent asthma attacks and other conditions involving inflammation of the lung tissues."
http://www.drugs.com/xq/cfm/pageid_0/htm_D00200A1.htm/type_mtm/tgid_17/bn_cromolyn%20sodium%20inhalation/qx/index.htm

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Cromolyn Sodium, What are the precautions when taking this medicine, Health and Age:"Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.

Tell healthcare provider if you are pregnant or plan on getting pregnant.

Tell healthcare provider if you are breast-feeding."
http://www.healthandage.com/html/res/com/ConsDrugs/CromolynSodiumcd.html

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Intal, Special Warnings About This Medication, Health Square:"Asthma symptoms may recur if the recommended dosage of Intal is reduced or discontinued. Intal has no role in the treatment of an acute asthmatic attack once it has begun. Obtain medical help immediately if you experience a severe attack.

If you have liver or kidney problems, your doctor may have to reduce the dosage or even take you off the drug altogether.

When using the capsules, you may accidentally inhale some powder, which can irritate your throat or make you cough. Try rinsing your mouth or taking a drink of water immediately before and/or after using the Spinhaler."
http://www.healthsquare.com/newrx/int1211.htm

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Cromolyn (Inhalation), Description, MEDLINEplus:"Cromolyn (KROE-moe-lin) is used to prevent the symptoms of asthma. When it is used regularly, cromolyn lessens the number and severity of asthma attacks by reducing inflammation in the lungs. Cromolyn is also used just before exposure to conditions or substances (for example, exercise, allergens, such as pollen, aspirin, chemicals, cold air, or air pollutants) that cause bronchospasm (wheezing or difficulty in breathing). Cromolyn will not help an asthma or bronchospasm attack that has already started.

Cromolyn may be used alone or with other asthma medicines, such as bronchodilators (medicines that open up narrowed breathing passages) or corticosteroids (cortisone-like medicines).

Cromolyn inhalation works by acting on certain inflammatory cells in the lungs to prevent them from releasing substances that cause asthma symptoms or bronchospasm."
U.S. National Library of Medicine
8600 Rockville Pike, Bethesda, MD 20894
custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202166.html

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Intal Capsule, How to use, Mythos.com:"Follow the directions for using this medication provided by your doctor or pharmacists. If you are taking the oral capsule, open capsule and pour contents into a glass of hot water. Stir until the contents are completely dissolved. Add cool water and drink all of the liquid. Do not mix with juice, milk, or carbonated beverages. If you are using the inhalation capsules, empty the contents of the capsule into the inhaler. The contents of one capsule are inhaled four times daily at regular intervals. If you are using the nebulizer solution, one ampule is administered four times per day at regular intervals, unless directed otherwise by your doctor. The effects of this medicine last three or four hours. It is important that you take your medication as directed and at the same times each day. Skipping doses and doubling doses can aggravate the condition. Do not keep outdated medicine or medicine no longer needed."
http://www.mythos.com/pharmacy/detail.aspx?I=3441&BM=3441&SP=Index_DrugName.aspx&P=1&L=A

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Cromolyn Sodium, Action/Kinetics, Nurses PDR:"Acts locally to inhibit the degranulation of sensitized mast cells that occurs after exposure to certain antigens. Prevents the release of histamine, slow-reacting substance of anaphylaxis, and other endogenous substances causing hypersensitivity reactions. When effective, reduces the number and intensity of asthmatic attacks as well as decreasing allergic reactions in the eye. No antihistaminic, anti-inflammatory, or bronchodilator effects and has no role in terminating an acute attack of asthma. After inhalation, some drug is absorbed systemically. t1/2: 81 min; from lungs: 60 min. About 50% excreted unchanged through the urine and 50% through the bile. When used in the eye, approximately 0.03% is absorbed. Onset, ophthalmic: Several days. Onset, nasal: Less than 1 week. Time to peak effect, nasal: Up to 4 weeks."
http://www.nursespdr.com/members/database/ndrhtml/cromolynsodium.html

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Intal, Most important fact about this drug, PDRhealth.com:"Intal does not help an acute asthma attack. When taken to prevent severe bronchial asthma, it can be 4 weeks before you feel its maximum benefit, though some people get relief sooner. Do not discontinue the inhalation capsules or nasal solution abruptly without the advice of your doctor."
http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/int1211.shtml

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Cromolyn Sodium, Indications, RXlist:"Intal Inhaler is a prophylactic agent indicated in the management of patients with bronchial asthma.

In patients whose symptoms are sufficiently frequent to require a continuous program of medication, Intal Inhaler is given by inhalation on a regular daily basis. (See DOSAGE AND ADMINISTRATION). The effect of Intal Inhaler is usually evident after several weeks of treatment, although some patients show an almost immediate response."
http://www.rxlist.com/cgi/generic2/cromolyn_ids.htm

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Cromolyn Sodium Inhalant and Nasal, Range and Frequency, Whole Health Md:"Inhalation aerosol-- To prevent asthma symptoms: Adults and children age 5 and older: 2 inhalations 4 times a day, 4 to 6 hours apart. To prevent bronchospasm: Adults and children age 5 and older: 2 inhalations at least 10 to 15 minutes before exercise or exposure. Inhalation solution-- To prevent asthma symptoms: Adults and children 2 and older: 20 mg, 4 times a day, 4 to 6 hours apart. Nasal solution-- For hay fever: Adults and children age 6 and older: 1 spray in each nostril 3 to 6 times a day."
http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,162,00.html

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