Tylenol Products and Related Conditions, Tylenol.com:"Tylenol is considered the pain reliever of choice by doctors and leading professional healthcare organizations. Used as directed, Tylenol has a superior safety profile compared with all other nonprescription pain relievers."
http://www.tylenol.com/

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Acetaminophen, Warning signs, Cincinnati Childrens Hospital Medical Center:"Unless directed by your child's doctor, babies should not take acetaminophen for longer than two days and small children should not take it longer than three days. Call your child's doctor if your child has a fever after this period of time, or if the symptoms get worse at any time."
Cincinnati Children's Hospital Medical Center 3333 Burnet Avenue, Cincinnati, Ohio 45229-3039 513-636-4200 | 1-800-344-2462
http://www.cincinnatichildrens.org/Health_Topics/Your_Childs_Health/Medications/A_-_E/acetaminophen.htm

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eMedicine Specialties: Emergency Medicine: Toxicology: Toxicity, Acetaminophen, emedicine.com:"Acetaminophen-induced hepatotoxicity is well recognized. Acetaminophen also is known as paracetamol and N-acetyl-p-aminophenol (APAP). It is found in the United States as 325-mg and 500-mg immediate-release tablets and as a 650-mg extended-release preparation. Various children's chewable, suspension, and elixir formulations of acetaminophen also are available. Furthermore, acetaminophen is found as a component of combination drugs such as propoxyphene-acetaminophen (eg, Darvocet) and oxycodone-acetaminophen (eg, Percocet)."
http://www.emedicine.com/emerg/topic819.htm

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HealthCentral - General Encyclopedia - Acetaminophen - oral, Description:"Acetaminophen is used as an analgesic (pain reliever) and as a antipyretic (decreases fever). It has no anti-inflammatory effect (reduces swelling). Check the ingredients of over-the-counter medication with this list, or consult a pharmacist to help identify how a medication is classified. See also: anti-inflammatory analgesics - oral; narcotic analgesics - oral; narcotic analgesics and aspirin - oral; narcotic analgesics and acetaminophen - oral; butalbital, acetaminophen, caffeine, and codeine; butalbital, aspirin, caffeine, and codeine."
http://www.healthcentral.com/news/NewsFullText.cfm?id=510072

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acetaminophen, Interactions with Dietary Supplements, Healthnotes, GNC.com:"N-acetyl cysteine (NAC) Hospitals use oral and intravenous N-acetyl cysteine (NAC) to treat liver damage induced by acetaminophen overdose poisoning.1 NAC is often administered intravenously by emergency room doctors. Oral NAC appears to be effective for acetaminophen toxicity. An uncontrolled trial compared intravenous NAC with oral NAC in children with acetaminophen poisoning and found that both methods were equally effective in reversing acetaminophen-induced liver toxicity.2 However, acetaminophen toxicity is a potential medical emergency, and should only be managed by qualified healthcare professionals."
http://www.gnc.com/health_notes/Drug/Acetaminophen.htm

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08-16-2001, Children's Acetaminophen Recalled, May Cause Liver Failure , Injuryboard.com:"Perrigo Company today announced that, in cooperation with the U.S. Food and Drug Administration (FDA), it is conducting a recall of 7,788 four-ounce bottles of cherry-flavored pain reliever suspension liquid with Lot Number 1AD0228. Perrigo determined that this lot may contain an excess of up to 29 percent over the labeled amount of acetaminophen. The product is being recalled because overdoses of acetaminophen can lead to severe health problems including liver toxicity and liver failure."
http://www.injuryboard.com/specificArticleFromSiteSearch.cfm?Article=725

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Acetaminophen Analgesia In Neonatal Circumcision: The Effect On Pain:"This study confirms that circumcision of the newborn causes severe and persistent pain. Acetaminophen was not found to ameliorate either the intra-operative or the immediate postoperative pain of circumcision, although it seems that it may provide some benefit after the postoperative period. Pediatrics 1994;93:641-646; neonatal circumcision, acetaminophen."
http://www.cirp.org/library/pain/howard/

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Acetaminophen (Systemic), commonly used brand names in the U.S., Medlineplus Health Information:"Aceta Elixir, Aceta Tablets, Acetaminophen Uniserts, Actamin, Actamin Extra, Actamin Super 2 Aminofen, Aminofen Max, Apacet Capsules, Apacet Elixir, Apacet Extra Strength Caplets, Apacet Extra Strength Tablets, Apacet, Infants', Apacet Regular Strength Tablets, Aspirin Free Anacin Maximum Strength Caplets, Aspirin Free Anacin Maximum Strength Gel Caplets, Aspirin Free Anacin Maximum Strength Tablets, Aspirin-Free Excedrin Caplets 2 Banesin, Bayer Select Maximum Strength Headache Pain Relief Formula 2 Dapa, Dapa X-S, Datril Extra-Strength, Feverall, Children's, Feverall, Infants', Feverall Junior Strength, Feverall Sprinkle Caps, Children's, Feverall Sprinkle Caps Junior Strength, Genapap Children's Elixir, Genapap Children's Tablets, Genapap Extra Strength Caplets, Genapap Extra Strength Tablets, Genapap, Infants', Genapap Regular Strength Tablets, Genebs Extra Strength Caplets, Genebs Regular Strength Tablets, Genebs X-Tra, Liquiprin Children's Elixir, Liquiprin Infants' Drops, Neopap, Oraphen-PD, Panadol, Children's, Panadol, Infants', Panadol Junior Strength Caplets, Panadol Maximum Strength Caplets, Panadol Maximum Strength Tablets, Phenaphen Caplets, Redutemp, Snaplets-FR, St. Joseph Aspirin-Free Fever Reducer for Children, Suppap-120, Suppap-325, Suppap-650, Tapanol Extra Strength Caplets, Tapanol Extra Strength Tablets, Tempra, Tempra D.S, Tempra, Infants', Tempra Syrup, Tylenol Arthritis Extended Relief Tylenol Children's Chewable Tablets, Tylenol Children's Elixir, Tylenol Children's Suspension Liquid, Tylenol Extra-Strength Adult Liquid Pain Reliever, Tylenol Extra Strength Caplets, Tylenol Extra Strength Gelcaps, Tylenol Extra Strength Tablets, Tylenol Infants' Drops, Tylenol Infants' Suspension Drops, Tylenol Junior Strength Caplets, Tylenol Junior Strength Chewable Tablets, Tylenol Regular Strength Caplets, Tylenol Regular Strength Tablets, Valorin, Valorin Extra"
U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894
U.S. National Library of Medicine
8600 Rockville Pike, Bethesda, MD 20894
custserv@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202001.html

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Acetaminophen (Apap, Paracetamol), Nursespdr.com:"Decreases fever by an effect on the hypothalamus leading to sweating and vasodilation. It also inhibits the effect of pyrogens on the hypothalamic heat-regulating centers. May cause analgesia by inhibiting CNS prostaglandin synthesis; however, due to minimal effects on peripheral prostaglandin synthesis, acetaminophen has no anti-inflammatory or uricosuric effects. Does not cause any anticoagulant effect or ulceration of the GI tract. Antipyretic and analgesic effects are comparable to those of aspirin."
Thomson Learning - Customer Service
PO Box 6904 Florence, KY 41022-6904
Tel: 800-354-9706 Fax: 800-487-8488 Email: esales@thomsonlearning.com
http://www.nursespdr.com/members/database/ndrhtml/acetaminophen.html

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acetaminophen, TylenolTM, Analgesic, Antipyretic, The P-I-E-N-O Parkinsn's List Drug Database:"Acetaminophen is the active metabolite of phenacetin. Acetaminophen possesses analgesic and antipyretic activity, however, some clinicians consider acetaminophen a poor analgesic. Since acetaminophen has no peripheral antiinflammatory activity, its efficacy as an analgesic may indeed be less than aspirin's in situations in which this action is desirable. Acetaminophen is preferred over aspirin as an analgesic/antipyretic for patients in whom aspirin is contraindicated, such as those who have a history of gastric ulcer or a coagulation disorder. Also, acetaminophen does not interfere with the actions of uricosuric agents as aspirin can. Acetaminophen was first used in clinical medicine in 1893, but widespread use began after its FDA approval in 1950."
http://www.parkinsons-information-exchange-network-online.com/drugdb/001.html

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Acetaminophen, Common Questions, Quick Answers: Pediatrics, Virtual Hospital:"What is acetaminophen? What are some brand names? What can I use it for? How should I use it? What is proper dosage? What are possible side effects? Where should I store it? When should I call the doctor?"
http://www.vh.org/Patients/IHB/Peds/CQQA/acetamin.htm

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Propoxyphene Napsylate and Acetaminophen, Clinical Pharmacology, Rxlist.com:"Propoxyphene is a centrally acting narcotic analgesic agent. Equimolar doses of propoxyphene hydrochloride or napsylate provide similar plasma concentrations. Following administration of 65, 130, or 195 mg of propoxyphene hydrochloride, the bioavailability of propoxyphene is equivalent to that of 100, 200, or 300 mg respectively of propoxyphene napsylate. Peak plasma concentrations of propoxyphene are reached in 2 to 2 ½ hours. After a 100-mg oral dose of propoxyphene napsylate, peak plasma levels of 0.05 to 0.1 mcg/ml are achieved. The napsylate salt tends to be absorbed more slowly than the hydrochloride. At or near therapeutic doses, this absorption difference is small when compared with that among subjects and among doses (for graphic illustration please see manufacturer's original package insert)."
http://www.rxlist.com/cgi/generic3/propoxnap_cp.htm

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Hydrocodone and Acetaminophen, Clinical Pharmacology, Rxlist.com:"Hydrocodone is a semisynthetic narcotic analgesic and antitussive with multiple actions qualitatively similar to those of codeine. Most of these involve the central nervous system and smooth muscle. The precise mechanism of action of hydrocodone and other opiates is not known, although it is believed to relate to the existence of opiate receptors in the central nervous system. In addition to analgesia, narcotics may produce drowsiness, changes in mood, and mental clouding."
http://www.rxlist.com/cgi/generic/hydrocod_cp.htm

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