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Toradol (Ketorolac) is contraindicated for some patients : Health Square: "Remember that Toradol has been known to cause peptic ulcers and bleeding. Contact your doctor immediately if you suspect a problem. This drug should be used with caution if you have kidney or liver disease. It may cause liver inflammation or kidney problems in some people. Toradol is not recommended for long-term use, since side effects increase over time. This medication should be taken for no more than 5 days. If you are an older adult, use this drug cautiously. Toradol can increase water retention. If you have heart disease or high blood pressure, use this drug with care. This medication can prolong bleeding time. If you are taking blood-thinning medication, take Toradol with caution."
http://www.healthsqr.com/newrx/TOR1453.HTM

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Ketorolac (Systemic), Medlineplus:"Ketorolac ( kee-toe-ROLE-ak) is used to relieve moderately severe pain, usually pain that occurs after an operation or other painful procedure. It belongs to the group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). Ketorolac is not a narcotic and is not habit-forming. It will not cause physical or mental dependence, as narcotics can. However, ketorolac is sometimes used together with a narcotic to provide better pain relief than either medicine used alone. Ketorolac has side effects that can be very dangerous. The risk of having a serious side effect increases with the dose of ketorolac and with the length of treatment. Therefore, ketorolac should not be used for more than 5 days. Before using this medicine, you should discuss with your doctor the good that this medicine can do as well as the risks of using it."
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202318.html

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Toradol, What is the most important information I should know about ketorolac ophthalmic? MSN Heatlh:"Do not touch the dropper to any surface, including your eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in your eye. • Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down your tear duct."
http://content.health.msn.com/content/drugs/3/4046_1320?bn=Acular

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Ketorolac tromethamine (Acular, Toradol), Uses, NursesPDR.com:"Short-term (up to 5 days) management of severe, acute pain that requires analgesia at the opiate level. Always initiate therapy with IV or IM followed by PO only as continuation treatment, if necessary. IM/IV: Ketorolac has been used with morphine and meperidine and shows an opioid-sharing effect. The combination can be used for break through pain. Ophthalmic: Relieve itching caused by seasonal allergic conjunctivitis. Reduce ocular pain and photophobia following incisional refractive surgery (Acular PF)."
http://www.nursespdr.com/members/database/ndrhtml/ketorolactromethamine.html

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Torodal (Ketorolac) clinical studies: Roche Pharmacuticals: "The analgesic efficacy of intramuscularly, intravenously and orally administered TORADOL was investigated in two postoperative pain models: general surgery (orthopedic, gynecologic and abdominal) and oral surgery (removal of impacted third molars). The studies were double-blind, single- and multiple-dose, parallel trial designs in patients with moderate to severe pain at baseline. TORADOLIV/IM was compared as follows: IM to meperidine or morphine administered intramuscularly and IV to morphine administered either directly IV or through a PCA (Patient-Controlled Analgesia) pump.Short-Term Use (up to 5 days) Studies: In the comparisons of intramuscular administration during the first hour, the onset of analgesic action was similar for TORADOL and the narcotics, but the duration of analgesia was longer with TORADOL than with the opioid comparators meperidine or morphine.In a multidose, postoperative (general surgery) double-blind trial of TORADOLIM 30 mg versus morphine 6 and 12 mg IM, each drug given on an as needed basis for up to 5 days, the overall analgesic effect of TORADOLIM 30 mg was between that of morphine 6 and 12 mg."
http://www.rocheusa.com/products/toradol/pi.html

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Overdose and comprehensive drug information for Toradol (Ketorolac): Rx List: "In controlled overdosage, daily doses of 360 mg of ketorolac tromethamine IV/IMgiven for five days (3 times the highest recommended dose), caused abdominal pain and peptic ulcers which healed after discontinuation of doses. Metabolic acidosis has been reported following intentional overdosage.Dialysis does not significantly clear ketorolac tromethamine from the blood stream.CATEGORIES: Conjunctivitis; Pain; Pregnancy Category B; FDA Class 1B (Modest Therapeutic Advantage); FDA Approved 1989 Nov FDA Drug Class: Analgesics, General; Analgesics-Non-Narcotic; NSAID; Ocular Anti-Infective/Anti-Inflammatory; Ophthalmics, MiscellaneousBRAND NAMES: Acular; Dolac; Kelac; Ketanov; Ketonic; Ketowin; Nodine; Tarasyn; Topadol; Toradol; Torolac; Torvin(Foreign brand names outside U.S. in italics)cost: $22.64 (Pain; Tablet; 10 mg; 4/day; 5 days"
http://www.rxlist.com/cgi/generic/ketor.htm

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Possible Side Effects while taking Toradol (Ketorolac): Walgreens Pharmacy: "SIDE EFFECTS, that may go away during treatment, include mild nausea, upset stomach, headache, drowsiness, dizziness, or diarrhea. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience decreased urination or blood in the urine, severe stomach pain or cramping, bloody or black tarry stools, vomiting blood or material that looks like coffee grounds, unusual bleeding or bruising, yellowing of the skin or eyes, dark urine or pale stools, unusual fatigue, skin rash, shortness of breath, difficulty breathing, or tightness in your chest. CONTACT YOUR DOCTOR IMMEDIATELY if you experience hives or swelling of hands, face, lips, eyes, throat, or tongue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. other effects not listed above, contact your doctor, nurse, or pharmacist"
http://www.walgreens.com/library/finddrug/druginfo.jhtml?_DARGS=%2Flibrary%2Ffinddrug%2Fdruginfo.jhtml.1_A&_DAV=13693

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Toradol, Acular, What is ketorolac ophthalmic? WebMD.com:"Ketorolac ophthalmic is in a class of drugs called nonsteroidal anti-inflammatory drugs. It reduces pain and inflammation in the eyes. • Ketorolac ophthalmic is used to relieve itching and inflammation of the eyes caused by allergic reactions. • Ketorolac ophthalmic may also be used for purposes other than those listed in this medication guide."
http://my.webmd.com/content/drugs/3/4046_1320?bn=Acular

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Warnings while taking Toradol (Ketorolac) : Yahoo Health: "WARNINGS Talk with your doctor before taking this medicine if you are pregnant, breastfeeding, or have heart disease, high blood pressure, liver or kidney disease, blood disorders, or ulcers or other stomach problems. You should not use this medicine for more than 5 days unless your doctor has told you to. Ulcers and stomach bleeding are sometimes caused by this type of medicine. These problems can happen without warning signs. You may need to see your doctor for regular check-ups while being treated with this medicine. Ketorolac may cause drowsiness and dizziness. Be careful if you are driving a car or using dangerous machinery."
http://health.yahoo.com/health/drugs/202318/overview.html

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