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Clonidine, David Riley, MD, eMedicine Journal, May 23 2001, Volume 2, Number 5: "Clonidine is a commonly used antihypertensive agent. Other reported clinical uses include treatment of opiate and alcohol withdrawal and control of atrial fibrillation with a rapid ventricular rate. It is also used as a pediatric preanesthetic, for pediatric postoperative pain management, treatment of migraine headaches, nicotine addiction, menopausal flushing, attention deficit disorder, Tourette syndrome, and pediatric panic and anxiety disorders."
http://www.emedicine.com/emerg/topic809.htm
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Clonidine (Catapres), Drug Interactions, lysine.pharm: "Tricyclic antidepressants. Concurrent treatment can block antihypertensive effect of clonidine."
http://lysine.pharm.utah.edu/netpharm/netpharm_00/druglist/clonidine.htm
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Clonidine Hydrochloride, Indications ,Rxlist: "Tablet: Clonidine hydrochloride is indicated in the treatment of hypertension. Clonidine hydrochloride may be employed alone or concomitantly with other antihypertensive agents.Epidural Injection: Epidural clonidine HCl is indicated in combination with opiates for the treatment of severe pain in cancer patients that is not adequately relieved by opioid analgesics alone. Epidural clonidine is more likely to be effective in patients with neuropathic pain than somatic or visceral pain (see CLINICAL STUDIES.)"
http://www.rxlist.com/cgi/generic/clonidin_ids.htm
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Clonidine (Catapres), Warnings and Precautions, What meds.com: "Children are more sensitive to Catapres than adults and may overdose on a normal adult dose of this medication. Catapres may impair coordination and alertness. Individuals taking Catapres should not drive or operate heavy machinery until its effects are known and do not interfere with such activities. Mental alertness is less likely to be affected when dosage is started small and gradually increased. Suddenly discontinuing Catapres may cause withdrawal symptoms such as headache, nervousness, agitation, tremor, confusion, and a rapid rise in blood pressure."
http://www.whatmeds.com/meds/clonidine.html
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Clonidine, Dosing, Medline Plus: "For oral dosage form (tablets): For high blood pressure: Adults--100 mcg (0.1 mg) two times a day. Your doctor may increase your dose up to 200 mcg (0.2 mg) to 600 mcg (0.6 mg) a day taken in divided doses. Children--Use and dose must be determined by your doctor. For transdermal dosage form (skin patch): For high blood pressure: Adults--One transdermal dosage system (skin patch) applied once a week. Children--Use and dose must be determined by your doctor."
http://www.nlm.nih.gov/medlineplus/druginfo/clonidinesystemic202152.html
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Clonidine (Catapres), C J Wilson, Pembroke College, Molecule of the Month, September 1999: "Two of the most interesting uses for the drug though are in the treatment of alcohol and nicotine withdrawl and in the treatment of ADD (Attention Deficit Disorder). For the treatment of ADD it has been found to reduce hyperactivity especially in children. However, tolerance can develop for the drug and can lead to withdrawl symptoms when taken off the drug. It is usually necessary to continue taking the drug for some time after the condition for which it was prescribed has been cured."
http://www.chem.ox.ac.uk/mom/clonidine/Clonidine.html
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Clonidine, Medications, ADHD Owner's Manual: "Clonidine is quite sedating, and should be used at the lowest effective dose. It should be tapered off and never stopped suddenly, as sudden cessation can cause rebound high blood pressure. The clonidine patch frequently is irritating to the skin, and may require use of a steroid cream and frequent movement of its location to avoid severe skin reactions."
http://www.edutechsbs.com/adhd/00019.htm
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Clonidine, Pharmacology, Tobacco Cessation Online Library: "Clonidine is used primarily as an antihypertensive medication (Fiore et al., 2000). Clonidine has not been approved by the FDA as an aid to smoking cessation (Fiore et al., 2000). Before advising tobacco users to quit with Clonidine, review the Treatment Specialist's role."
http://www.azpntr.org/resources/content_pages/Pharmacology/pt10.htm
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Clonidine Hydrocloride, (Catapres), Uses, Nurses PDR Resourse Center: "Oral, Transdermal: Mild to moderate hypertension. A diuretic or other antihypertensive drugs, or both, are often used concomitantly. Treat spasticity. Investigational: Alcohol withdrawal, atrial fibrillation, attention deficit hyperactivity disorder, constitutional growth delay in children, cyclosporine-associated nephrotoxicity, diabetic diarrhea, Gilles de la Tourette's syndrome, hyperhidrosis, hypertensive emergencies, mania, menopausal flushing, opiate detoxification, diagnosis of pheochromocytoma, postherpetic neuralgia, psychosis in schizophrenia, reduce allergen-induced inflammatory reactions in extrinsic asthma, restless leg syndrome, facilitate smoking cessation, ulcerative colitis. Epidural: With opiates for severe pain in cancer clients not relieved by opiate analgesics alone. Most effective for neuropathic pain."
http://www.nursespdr.com/members/database/ndrhtml/clonidinehydrochloride.html
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