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Megestrol acetate (Megace) The CancerBACUP factsheet:"Megace (also known as Megestrol acetate) is a man-made substance called progestin which is similar to the female hormone progesterone. It is mainly used in the treatment of breast cancer. Its other uses are described at the end of this factsheet."
http://www.cancerbacup.org.uk/info/megestrol.htm
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Megestrol, Healthanswers.com:"MEGESTROL (MegaceŽ, PallaceŽ) is similar to the natural female hormone called progesterone. Megestrol tablets are used for treating breast cancer and endometrial cancer. Generic megestrol tablets are available."
http://www.healthanswers.com/Library/Gsm/patinfo.asp?drugid=370
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MEGESTEROL, HIV Dent:"A Commonly Used Medication for HIV & AIDS Patients:
http://www.hivdent.org/drugs/MEGESTEROL.htm
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Appetite Stimulation:
Medicinal Marijuana, Marinol, and Megace, Medibolics:"Appetite stimulants can be an important part of the optimal approach to increasing lean body mass in HIV. However, all appetite stimulants are not equal in their effects on your overall health and well-being. The first drug used for appetite in the early years of AIDS was Megace. The Medibolics article on Megace showed us that Megace should probably be relegated to the status of the problematic dinosaur drug that it is."
http://www.medibolics.com/Marinol2.htm
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Megace, PDR:"MEGACE is indicated for the palliative treatment of advanced carcinoma of the breast or endometrium (i.e., recurrent, inoperable, or metastatic disease). It should not be used in lieu of currently accepted procedures such as surgery, radiation, or chemotherapy."
http://www.healthandage.com/html/res/pdr/html/10500600.htm
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Megestrol, MegaceŽ, PallaceŽ, Texas Cancer Online:"Megestrol, MegaceŽ, PallaceŽ is similar to the natural female hormone called progesterone. Megestrol tablets are used for treating breast cancer and endometrial cancer. The oral suspension is used to treat loss of appetite, weight loss, and malnutrition that may occur with certain conditions."
http://www.jasper-web.com/texascanceronline/Drugs/megace.htm
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Articles:
Megace Caution AIDS TREATMENT NEWS Issue # 77, April 21, 1989"James Kahn, M.D., the principal investigator of this study was notified earlier this month by the manufacturer, Bristol-Myers, that one participant in another Megace study had developed a severe rash covering most of his body after eight days of Megace, 1200 mg each day. The rash was later diagnosed as Stevens-Johnson Syndrome. It was treated with benadryl and steroids and resolved slowly. Because the participant had a diagnosis of AIDS and had been receiving other medications, there is not a conclusive link between the rash and Megace. Nevertheless, Dr. Kahn felt that we should caution people on Megace to be aware of any allergic reactions (which must be seen immediately by a physician). Dr. Kahn can be reached at 415/821-5531."
http://www.aegis.com/pubs/atn/1989/ATN07703.html
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Megace to Stimulate Appetite, Gay Men's Health Crisis Treatment Issues, Vol. 5, No. 9, December 1991:"Megace is the brand name of megestrol acetate, a synthetic substance derived from the female hormone, progesterone. The drug is marketed by Bristol-Myers Company for the treatment of breast cancer which has spread to other parts of the body. Another possible use of Megace is to stimulate appetite in order to produce weight gain. The actual way Megace works in appetite stimulation is unclear. Some experiments seem to indicate that the drug plays a role in fat synthesis in the body."
http://www.aegis.com/pubs/gmhc/1991/GM050910.html
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