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Warfarin, Coumadin, Anticoagulants,
Blood Thinners, Drug Therapy Links

BRAND NAMES: Coumadin; Aldocumar; Athrombin; Coumadan Sodico; Coumadine; Dimantil; Farin; Marevam; Marevan; Orfarin; Panwarfin; Simarc-2; Sofarin; UniWarfin; Waran; Warfarina; Warfil 5; Warfilone (Foreign Brand names outside U.S. in italics)

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Blood Thinning With Warfarin (Coumadin), heartpoint.com:"Warfarin is a compound of significant medical importance. Over the last 40 years, thousands have used it, and used it safely and effectively, to prevent strokes, heart attacks, clots in the legs (deep venous thrombosis), clots to the lungs (pulmonary emboli), and other disorders. It decreases the tendency of the blood to clot, and is very potent in doing so. It is a medication that must be taken with great care . . . it's not difficult, but it is important to "follow the rules" to maximize the benefits and minimize the potential adverse reactions."
http://www.heartpoint.com/coumadin.html

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Coumadin.com (Bristol Myers Squibb):"It is recommended that COUMADIN® therapy be initiated with a dose of 2 to 5 mg per day with dosage adjustments based on the results of Prothrombin Time (PT)/International Normalized Ratio (INR) determinations. Most patients are satisfactorily maintained at a dose of 2 to 10 mg daily. The dosing of COUMADIN® must be individualized according to patient’s sensitivity to the drug as indicated by the PT/INR.8 Use of a large loading dose may increase the incidence of hemorrhagic and other complications, and may give a false sense of full anticoagulation in early treatment. Use of large loading doses does not offer more rapid protection against thrombi formation, and is not recommended. Low initiation doses are recommended for elderly and/or debilitated patients and patients with potential to exhibit greater than expected PT/INR response to COUMADIN®."
http://www.coumadin.com/hcp/hcpPI.shtm

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Coumadin, The Heart Surgery Forum:"Anticoagulation is a term which means "reducing the bloods potential to clot". Many people interchange the expression "thinning of the blood" with the term "anticoagulation". In fact, this later term is so common that anticoagulant medications are usually spoken of as blood thinners. However, anticoagulants do not really "thin out", disolve, or dilute any aspect of the blood. The role of "blood thinners" rests solely with their unique ability to reduce clotting of the blood, and thus reduce the risk of certain conditions which arise from abnormal clot formation."
http://www.hsforum.com/stories/storyReader$1504

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THE COUMADIN® COOKBOOK A complete guide to healthy meals when taking Coumadin®:"Patients on COUMADIN® have always had to pay attention to the Vitamin K content in their foods. "The COUMADIN® Cookbook" provides guidelines for stabilizing daily Vitamin K intake to patients on COUMADIN®. In addition to clear directions for preparing a variety of tasty dishes, each recipe in the book gives the number of micrograms of Vitamin K contained per serving. This cookbook is written with the viewpoint of the patient in mind. With the use of the cookbook, it should be easier for the patient to eat a wide variety of healthy foods AND consume roughly the same amount of vitamin K each day."
http://members.aol.com/cmcookbook/

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Patient Information Questions and Answers About Your Anticoagulant Medication:"Anticoagulants are medicines that are prescribed specifically to prevent and/or treat thrombosis. Thrombosis is the medical word for the formation of a clot inside your blood vessels. There are two types of anticoagulants."
http://is.dal.ca/~mscully/patient.html

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Warfarin and NSAIDS
http://www.shef.ac.uk/uni/projects/wrp/warfnsai.html

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Created on July 24, 1999

Last updated by Andrew Lopez, RN March 3, 2005
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