Nursing & Healthcare Directories on: The Nursefriendly
Prescription Drugs, Medications, Medicines
Rheumatoid Arthritis, Biological Response Modifiers,
Anakinra, Kineret

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Kineret (Anakinra), How does it work, ArthritisInsight.com:"Designed specifically to treat inflammatory arthritis, it blocks a protein called Interleukin, a major player in the inflammatory process. By blocking IL-1, Kineret inhibits the inflammatory response in RA including pain."
http://arthritisinsight.com/medical/meds/kineret.html

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ACR: Kineret (Anakinra) Effective in Treatment for Rheumatoid Arthritis, Novewmber 16, 2001, Doctor's Guide:"Kineret is the first interleukin-1 receptor antagonist to treat the signs and symptoms of moderate to severe RA in patients suffering from the disease who have failed to derive benefits from other disease-modifying anti-rheumatic drugs (DMARDs). The drug can be used alone or in conjunction with other DMARDs, with the exception of tumor necrosis factor (TNF) blocking agents."
http://www.pslgroup.com/dg/20DEE6.htm

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ANAKINRA, What is anakinra, Drugs.com:"Anakinra reduces the actions of chemicals in the body that are involved in inflammatory and immune responses.
Anakinra is used to treat the symptoms of moderate to severe rheumatoid arthritis in patients who have had an inadequate response to one or more antirheumatic drugs."
http://www.drugs.com/xq/cfm/pageID_0/htm_d04775A1.htm/bn_anakinra/qx/index.htm

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Kineret(Anakinra), Who is this for, E Drug Digest:"This medication is used to reduce the pain and swelling associated with rheumatoid arthritis in patients 18 years or older who have had an inadequate response to disease modifying antirheumatic drugs (DMARDs)."
http://www.drugdigest.org/DD/PrintablePages/Monograph/1,7765,550910,00.html

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Kineret, Why is this drug prescribed, Health Square:"Kineret is used to relieve the symptoms of rheumatoid arthritis. It is usually prescribed after other antirheumatic drugs have failed to make an improvement. Kineret can be prescribed alone or in combination with other drugs for rheumatoid arthritis.

Kineret works by blocking the effects of interleukin-1, an inflammatory compound released by the immune system. While fighting inflammation, Kineret may also affect the immune system's ability to fight infection."
http://www.healthsquare.com/newrx/kin1604.htm

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Kineret™(Anakinra), How does Kineret™ work, Kineretrx.com:"Kineret™ is a man-made protein that is similar to a naturally occurring protein called Interleukin-1 receptor antagonist (IL-1Ra) found in the body. In people with rheumatoid arthritis (RA), the body produces too much of certain proteins that lead to joint damage. One of these proteins is called Interleukin-1 (IL-1). Too much IL-1 contributes to the pain, swelling, and stiffness associated with RA. Kineret™ can block the action of IL-1."
http://www.kineretrx.com/patient/product_information.jsp

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Kineret™ (anakinra), INDICATIONS AND USAGE, KuwaitPharmacy.com:" Kineret™ is indicated for the reduction in signs and symptoms of moderately to severely active rheumatoid arthritis, in patients 18 years of age or older who have failed 1 or more disease modifying antirheumatic drugs (DMARDs). Kineret™ can be used alone or in combination with DMARDs other than Tumor Necrosis Factor (TNF) blocking agents (See WARNINGS)."
http://www.kuwaitpharmacy.com/newdr/kineret.html

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Anakinra (Systemic), Description, MEDLINEplus:"Anakinra ( an-a-KIN-rah) is used to treat moderate to severe symptoms of rheumatoid arthritis. It may relieve redness, pain, tenderness, and warmth in hands, feet, wrists, shoulders, elbows, and ankles. This medicine is used in patients 18 years of age or older. Anakinra will not cure the disease, but will help with the symptoms as long as you continue to take it."
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/500349.html

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Anakinra (Kineret), WHAT'S NEW IN DRUGS, March 2002, RA Sufferers Have A More Selective Treatment Option, Nurses PDR:"Adults with moderate to severe rheumatoid arthritis (RA) that doesn’t respond to disease-modifying antirheumatic drugs (DMARDs) have a new alternative: anakinra (Kineret). The new agent selectively blocks interleukin-1, an important mediator of inflammation and joint destruction. RA patients have an excess of this protein. Anakinra is administered once daily by subcutaneous injection into the stomach, arm, or thigh, and it can be used alone or in combination with other DMARDs."
http://www.nursespdr.com/members/news/rn_mar02.html

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Kineret (Anakinra), RemedyFind.com:"Kineret (Anakinra) is a newly approved biologic therapy for rheumatoid arthritis which works by blocking an inflammatory molecule called Interleukin-1 (IL-1).

Interleukin-1 (IL-1) is a mediator of joint inflammation and destruction. When IL-1 binds to its receptor, the immune system starts a chemical reaction to fight off infections and decrease tissue injury and cell death."
http://remedyfind.com/rm-3029-Kineret.asp

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